Featuring an engrossing single-player campaign with lavishly gory details, Infected unlocks the world of Wi-Fi via exciting multiplayer modes. To participate in multiplayer combat, players create their own character or avatar. Those who are victorious in combat can "infect" the loser's PSP system with their avatar and gain ranking points. Avatars can be defeated through a variety of methods, as well as passed along from player to player thus creating a viral chain letter of attack.

1. Infect the world – spread your unique avatar like a virus to other players' PSP systems via exciting multiplayer modes such as Deathmatch and Team Deathmatch
2. Through multiplayer victories, players can potentially spread their avatars from player to player around the globe
3. Form clans with shared uniforms, spreading the same unique virus to the lesser skilled
4. Ultra-fast paced, two-gun action in the streets of New York
5. Access a huge arsenal of guns and viral weapons, as well as special weapons like air strikes and fire trails that ignite chains of Infected
6. Set off massive chain reactions of exploding Infected, showering the streets with blood.